Antimicrobial resistance in bacteria from horses: Epidemiology of antimicrobial resistance


poses a significant threat to the continued successful use of antimicrobial agents for the treatment of . While the epidemiology of in bacteria from man has been studied extensively, less work has been undertaken in companion animals, particularly .

is prevalent in bacteria from horses, particularly , and many of the most significant resistance mechanisms have been identified in equine isolates.

Methicillin-resistant has been identified as a cause of infections, with a low prevalence of nasal carriage by horses in the community but higher for hospitalised horses. Molecular characterisation has shown methicillin-resistant strains either to be predominantly of types associated with horses or of sequence type ST398.

Antimicrobial-resistant (including multidrug-resistant and extended spectrum β-lactamase-producing isolates) have caused infections and been documented in faecal carriage by horses, with many significant resistance mechanisms identified. More sporadic reports and molecular characterisation exist for resistance in other bacteria such as enterococci, Salmonella, Acinetobacter and Pseudomonas species. Limited work has been undertaken evaluating risk factors and much of the epidemiology of antimicrobial resistance in bacteria from horses remains to be determined.

Authors: T. W. Maddox. Read full text here.

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